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Sponsored| Name | Address | City |
|---|---|---|
| Start Bupe PLLC | 3541 Randolph Rd STE 102 | Charlotte |
| Eastover Psychological and Psychiatric Group PA | 3303 Latrobe Drive | Charlotte |
| Zenith Hope Center | 508 Eastway Drive Suite A | Charlotte |
| Addiction, Treatment, Recovery and Education, PLLC | 5105 Monroe Rd Suite C | Charlotte |
| South Charlotte VA Clinic | 3506 West Tyvola Road | Charlotte |
| Atrium Health Addiction Services | 447 Billingsley Rd A | Charlotte |
| Ascend Health PLLC – Suboxone Clinic | 10831 Pineville Rd Ste 9 | Charlotte |
| Neal S. Taub, MD | 3535 Randolph Road Suite 208 | Charlotte |
| Emily Hayes | 6115 Hickory Grove Rd | Charlotte |
| New Season Treatment Center – Charlotte | 3315 Wilkinson Blvd | Charlotte |
| Advene Health Group | 1421 Orchard Lake Dr Suite C | Charlotte |
| Eastowne Family Physicians | 4115 The Plaza | Charlotte |
| Queen City Treatment Center | 4949A Albemarle Rd | Charlotte |
| Crossroads Treatment Centers Shelby | 1895 East Dixon Blvd | Shelby |
| Rowan Treatment Centers | 1504 Jake Alexander BLVD W | Salisbury |
| McLeod Addictive Diseases Center – Gastonia | 549 Cox Road | Gastonia |
| McLeod Centers For Wellbeing Concord | 300 Copperfield Blvd. | Concord |
| New Season Treatment Center – York County | 377 Rubin Center Drive Suite 101 | Fort Mill |
| New Season Treatment Center – Gastonia | 1455 E Franklin Blvd | Gastonia |
| Rock Hill Treatment Specialists | 1274 East Main St. | Rock Hill |
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Medication treatment for opioid use disorder in Charlotte
Charlotte and the rest of Mecklenburg County are served by both opioid treatment programs, where methadone is dispensed, and office-based prescribers who handle buprenorphine and naltrexone, so most people here can reach care without leaving the county. The listings above show providers near you. Treatment for opioid use disorder (OUD) centers on three medications, methadone, buprenorphine (including Suboxone), and naltrexone, and a clinician helps you decide which one fits. If you are deciding today, call a provider on this page or the helpline to ask about the soonest intake.
Your medication options and where each one is available
Three medications are approved for opioid use disorder, and where you get them depends on which one you and your clinician choose. Methadone for OUD is dispensed only through a licensed opioid treatment program (OTP), not a regular pharmacy, so it involves going to a clinic, at least at first. Buprenorphine, which includes Suboxone and other buprenorphine-naloxone products as well as the extended-release monthly injection Sublocade, works differently: since 2023 any clinician with a standard DEA registration can prescribe it, so you can get it in a doctor’s office (office-based opioid treatment, or OBOT) and fill it at a pharmacy, or through an OTP. Naltrexone, including the monthly Vivitrol injection, is not a controlled substance and any licensed provider can prescribe it, but you have to be off opioids for a set time first to avoid sudden withdrawal. If you want a fuller side-by-side of the two most-used options, see how methadone and Suboxone compare. None of these is the “right” choice for everyone; that decision is yours to make with a clinician.
Starting treatment: intake and the first dose
The first visit is an assessment. A provider reviews your opioid use, health history, and what you want from treatment, then talks through which medication to start. With most of Charlotte’s illicit opioid supply now involving fentanyl, the timing of a first buprenorphine dose matters: starting Suboxone too soon after fentanyl can trigger sudden, severe withdrawal (called precipitated withdrawal), so a clinician plans that first dose with you rather than rushing it. Methadone induction is handled inside the OTP. Some local programs offer same-day or walk-in starts, though that varies by provider, so ask when you call. For more on starting medication after fentanyl, see methadone treatment for fentanyl addiction.
Take-home doses and telehealth: what current rules allow
If you are transferring into Charlotte or restarting treatment, the access rules changed in your favor. Federal rules updated in 2024 expanded take-home methadone to as much as a 28-day supply for patients who are stable in treatment, with smaller amounts earlier on, and the program decides eligibility based on how you are doing. Those same rules let treatment begin by telehealth and authorized mobile medication units. As of June 2026, buprenorphine can be started through telehealth, including by phone in many cases, without a prior in-person visit; these flexibilities run through the end of 2026 and are still being finalized, so confirm what is current with a provider. Methadone for OUD is still dispensed through an OTP, though some programs can begin treatment with a telehealth visit. Staying on a steady dose is part of why treatment works, which is worth understanding before you taper anything; see why your methadone dose matters and how long-term methadone treatment functions as ongoing care.
Paying for treatment in Mecklenburg County
NC Medicaid covers all three opioid use disorder medications, methadone, buprenorphine, and naltrexone, with methadone provided through opioid treatment programs and Vivitrol and buprenorphine covered as well, though buprenorphine products require prior authorization (NC Medicaid State Plan, effective October 2025). For most Mecklenburg County residents with serious substance use needs, behavioral health and substance use services run through a Behavioral Health and I/DD Tailored Plan, which launched statewide on July 1, 2024; the plan serving Mecklenburg County is Alliance Health, which also manages state-funded services for people who are uninsured. Private insurance and Medicare also cover medication treatment, and many programs offer self-pay or sliding-scale options. Cost is often the first worry, so ask each provider directly what they accept; the listings above are the place to start.
The overdose picture in Charlotte, and why treatment is the response
Mecklenburg County’s public health dashboard recorded 1,387 overdose deaths since 2019, with about 27.8% attributed to fentanyl, which is increasingly mixed into cocaine and counterfeit pills (Axios Charlotte, 2025). The burden is not spread evenly: the 28208 ZIP code in west Charlotte logged the most overdose-related emergency department visits in the county, and fatal overdoses rose 200% among Black and Hispanic residents between 2019 and 2023 (Mecklenburg County Public Health, 2025). There is also real progress. In 2024, fatal overdoses fell for the first time in six years across racial groups, and county overdose ED visits dropped from more than 2,500 in 2023 to under 1,900 (WFAE, 2025), a decline local officials tie to wider naloxone access and treatment. Effective medication treatment is available across Charlotte, and the listings above connect you to it. For background on the condition itself, see opioid addiction.
Pregnancy, reentry, and other specific situations
Some situations need a provider with particular experience. For pregnant patients, medication treatment with methadone or buprenorphine is the recommended standard of care, and starting or staying on medication is safer for both parent and baby than stopping; programs plan for neonatal opioid withdrawal syndrome (NOWS) and coordinate care, and treatment is meant to support a family, not threaten it. See methadone and pregnancy for more. Mecklenburg County has also directed opioid settlement money toward people leaving incarceration, including treatment inside the Mecklenburg County Detention Center and reentry support as people return to the community (Mecklenburg County, 2024), which matters if a court, probation, or a recent release is part of your situation. Conversations with a provider are confidential, and if you are helping someone you love, information for families walks through how to start.
Naloxone and overdose safety
Naloxone, the medication that reverses an opioid overdose, is widely available in North Carolina. Under a statewide standing order in place since 2016, you can get it at most pharmacies without an individual prescription, and Mecklenburg County distributed 16,968 doses in 2024 through opioid settlement funding, including leave-behind kits handed out by MEDIC, the county EMS agency, after overdose calls (Mecklenburg County Public Health, 2025). North Carolina’s 911 Good Samaritan law also protects people who call for help during an overdose from certain charges. A return to use can happen and is a manageable part of treatment, not a failure, so keeping naloxone on hand is simply good planning. For more on the risk, see overdose and methadone safety.
Common questions about treatment in Charlotte
Is methadone or Suboxone better?
Neither is better for everyone. Methadone, available only through an opioid treatment program, often suits people who want daily structure or have not done well on other options; buprenorphine (Suboxone) can be prescribed in an office and filled at a pharmacy, which fits people who want fewer visits. A clinician helps you weigh them based on your history and what daily life you want.
Do I have to go to a clinic every day?
Not necessarily. Methadone starts with more frequent visits, but federal rules updated in 2024 allow take-home supplies of up to 28 days once you are stable, decided by the program. Buprenorphine and naltrexone are generally prescribed for use at home from the start.
Can I start treatment the same week?
Often, yes. Some Charlotte-area programs offer same-day or walk-in intake, and buprenorphine can frequently be started by telehealth. Availability varies, so call a provider on this page or the helpline to ask about the soonest opening.
Will my insurance cover it?
NC Medicaid covers all three medications, with buprenorphine requiring prior authorization (NC Medicaid, 2025). Private insurance and Medicare typically cover treatment as well. Confirm specifics with the provider you choose.
Can I get addicted to methadone?
Methadone creates physical dependence, which is not the same as continued opioid use disorder; taken as prescribed, it stabilizes you and is considered legitimate, effective treatment, much like medication for any other chronic condition.
Page details and disclosures
Last reviewed June 2026.
Sources: Axios Charlotte, Mecklenburg County overdose data (2025); Mecklenburg County Public Health, overdose and naloxone distribution (2025); WFAE, 2024 overdose decline (2025); QC News, opioid settlement spending (2024); NC Medicaid State Plan, MAT assurances (2025); NC Medicaid, Behavioral Health and I/DD Tailored Plans; NCDHHS LME/MCO Directory (Alliance Health, Mecklenburg County); NC Harm Reduction Coalition, Good Samaritan and naloxone law; DEA, telemedicine flexibilities through 2026 (2025); SAMHSA, buprenorphine telemedicine rule.
Methadone Centers is a treatment-discovery and education resource, not a treatment provider, and does not offer medical advice; decisions about medication and care should be made with a licensed clinician.
The helpline featured on this site is operated by a sponsored partner. Calls may be answered by an organization that supports this site, and you are never obligated to use any provider listed here.