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Houston, a city with an area of 1,651 km2 and a 2019 population estimated at 2,320,268, is one of the largest and most populated cities in the U.S. It is the most populous city in Texas and the Southern United States, generally. People who need medical assistance to overcome opioid addiction may visit any methadone clinic Houston for proper medication-assisted treatment. Methadone is a long-acting medication-assisted treatment for the correction of opioid use disorder. Approved by the Food and Drug Administration, if used as prescribed by a medication-assisted treatment practitioner, it is an effective opioid agonist. As it is in other states, all methadone clinics in Texas are required to be accredited by the Substance Abuse and Mental Health Services Administration. A combination of methadone with counseling and behavioral therapies is effective in recovering from opioid use disorders. Treatment is tailored for individuals, therefore, patients are required to share their full health history with medication-assisted treatment practitioners, who prescribe the use of methadone based on their observation, and adjust the doses with time. Duration of treatment could range from 12 months, which is considered short term, to many years. In some cases, treatment could go on for life. Methadone is available in diskettes form, liquid, and powder.