Spartanburg, the county seat of Spartanburg County, is rated the twelfth most populous city in the U.S. state of South Carolina. As of 2018, it had a population estimated at 37,644, which makes it a possible home to various individuals passing through opioid addiction. The city has a total area of 51.49 km² of which 0.47% is water. There are some Spartanburg methadone clinics where locals experiencing opioid addiction may get medical treatment. Reliance, physically or psychologically, comes with some adverse effects but people suffering from it do not find it easy to quit because of the painful symptoms of withdrawal and uncontrollable craving. Methadone is one of the three approved medications for the medical treatment of such conditions. Methadone is an opioid agonist that calms the program enrollee, minimizes cravings, and blocks the psychological and physical effects of opioids in the body. The drug, if taken in compliance with the instructions from a medication-assisted treatment practitioner, is safe. Most methadone clinics in South Carolina, as it is done in other places, encourage the program enrollees to partake in behavioral therapies and counseling while the program is on. The combination of medication and psychosocial support is important because opiate addiction could have caused both some psychological damages that should be corrected.