Knoxville, the county seat of Knox County, is rated the third-largest city in the U.S state of Tennessee. With a 2019 population estimated at 187,603, Tennessee is certainly home to several people who are suffering from opioid dependency. Fortunately, there are some methadone clinics in its total area of 270 km². Inhabitants of Knoxville or nearby cities may medically treat opiate addiction at any methadone clinic Knoxville TN. People who take opioids once have the likelihood of going for more because it gives euphoria. However, its effects are short term, which makes people take it frequently even when there are adverse effects. The problem gets serious when people attempt to withdraw. Withdrawal could cause so much craving and physical pains that people may be pushed back to opioids. Methadone, a harmless medication, is an opioid agonist. The medication minimizes craving and relieves pains. It treats the physical and psychological effects of opioids in the body. The drug is safe and effective, but it should not be taken without the guidance of a medication-assisted treatment professional. Methadone clinics in Tennessee, as done in most places around the world, inform the program enrollees about the need to combine medication with psychosocial support.