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Clarksville, the county seat of Montgomery County, is rated the fifth largest city in the U.S. state of Tennessee. It has a total area of 247.4 km² on which some methadone clinics could be found. Considering how fast opioid use disorder has cut across most places in the world, any city with over a hundred thousand population like Clarksville is certainly home to several people experiencing opiate addiction. Locals may treat it at any methadone clinic in Clarksville. Opioid relieves pains and gives euphoria. However, its effects are short term, which makes people consume it occasionally to enjoy the effects. Opioids have some adverse effects but people rely on it psychologically or physically because quitting is not easy; the symptoms of withdrawal can be disturbing and painful. Methadone is an opioid agonist that blunts withdrawal symptoms in the body as well as the adverse effects of opioids. The medication calms the body and reduces pain. Methadone is approved by the Food and Drug Administration. The drug is so vital that it earned a slot on the World Health Organization’s list of essential medications. Methadone clinics in Tennessee and most other places, require the patients to partake in behavioral therapies to treat the adverse psychological effects opioids might have caused.