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Monroe, a city with a total area of 85.21 km² of which 11.46% is water, is the eighth-largest city in Louisiana. Louisiana, because of how fast opioid addiction has spread throughout almost every part of the world, is considered a possible home to a number of people experiencing opioid dependency. As of 2018, the city had a population estimated at 47,877. People who need to treat opioid use disorder in and around the city may visit any Monroe methadone clinic. Methadone clinics have medication-assisted treatment practitioners who are trained to medically assist people who are experiencing opiate dependence. Methadone is the drug they use, but it is usually combined with psychosocial support to correct the negative psychological effects opioid use could have caused. Methadone is safe and efficient. It has been successfully used for a number of cases and it has been added to the World Health Organization’s list of essential medications. Although it is essential, methadone, like every other drug should not be abused because it could cause some negative effects. To avoid such a situation and to prevent it from being diverted to the illicit market, methadone is regulated, only available under the supervision of a health provider in a methadone clinic. All methadone clinics in Louisiana are required to register with the Drug Enforcement Administration.