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Sponsored| Name | Address | City |
|---|---|---|
| Corner of Hope Recovery Center | 1813 Standard Ave | Louisville |
| Compserv Health Resources Inc | 101 N 7th St | Louisville |
| Nulease Medical Solutions | 5722 Outer Loop | Louisville |
| Kentucky Recovery | 501 Baxter Avenue Suite 125 | Louisville |
| Praxis of Louisville by Landmark Recovery | 4418 Malcolm Ave | Louisville |
| CleanSlate Outpatient Addiction Medicine Louisville | 210 E Gray St UNIT 803 | Louisville |
| Landmark Recovery of Louisville | 4112 Fern Valley Rd suite a | Louisville |
| Crossroads | Louisville | 1700 Cargo Court | Louisville |
| Medication Oriented Recovery and Enhancement (MORE) Center | 4500 Churchman Ave Suite 300 | Louisville |
| Louisville VA Medical Center | 800 Zorn Ave | Louisville |
| Louisville Addiction Center | 827 E Market St | Louisville |
| Spero Health – Suboxone and Vivitrol | 1017 Dupont Road | Louisville |
| Medmark Treatment Centers – BayMark Health Servs of Kentucky Inc | 4922 Poplar Level Road | Louisville |
| Center for Behavioral Health – Louisville | 1402-A Browns Lane | Louisville |
| Seven Counties Services | 600 S Preston St | Louisville |
| New Leaf Clinic | 215 W Breckinridge St | Louisville |
| Care Center | 3711 Bells Ln | Louisville |
| Cleanse Clinic Downtown | 645 Roy Wilkins Ave | Louisville |
| Sunrise Recovery | 1610 Blackiston View Drive | Clarksville |
| Southern Indiana Comprehensive Treatment Center | 7509 Charlestown Pike | Charlestown |
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Finding opioid use disorder treatment in Louisville
Louisville is the largest city in Kentucky and the seat of Jefferson County, and people here can reach both kinds of medication treatment for opioid use disorder (OUD): opioid treatment programs that dispense methadone, and office-based clinicians who prescribe buprenorphine or naltrexone. The three FDA-approved medications, methadone, buprenorphine (including Suboxone), and naltrexone (including Vivitrol), are all available in the metro, and telehealth now fills gaps for buprenorphine. The provider listings on this page show local options you can call directly, and the helpline is there if you would rather talk it through first.
Your medication options and where each one comes from
Three medications treat OUD, and where you get them depends on which one you and a clinician choose. Methadone for OUD is dispensed only through a licensed opioid treatment program (OTP), not a regular pharmacy, so it involves going to a clinic, at least at first. Buprenorphine, which most people know as Suboxone (a buprenorphine-naloxone combination), can be prescribed in a doctor’s office and filled at a pharmacy, or provided inside an OTP. It also comes as an extended-release monthly injection (Sublocade). Naltrexone, including the monthly Vivitrol injection, is not an opioid and can be prescribed by any licensed provider, but it is started only after you have been off opioids for a set period, which a clinician will help you time. Buprenorphine and naltrexone can be delivered through office-based opioid treatment (OBOT), while methadone stays within the OTP system. If you are weighing the choice, it helps to read how methadone and Suboxone compare and to look at the basics of how methadone works before you call. The decision is one to make with a clinician, not alone.
Starting treatment and what the first visit looks like
The first step is usually an intake assessment, where a provider reviews your history, confirms a diagnosis, and discusses which medication fits. Bring an ID and insurance information if you have them, but not having insurance does not stop you from being seen. Because so much of the street supply in this area is fentanyl, timing matters when starting buprenorphine: taking it too soon after fentanyl can trigger sudden, severe withdrawal (precipitated withdrawal), so a clinician plans when you take your first dose. Some programs offer same-day or next-day starts. Methadone is started and dispensed at an OTP, and some programs can begin treatment after a telehealth visit. You can read more about starting methadone treatment when fentanyl is involved and about opioid use disorder treatment generally as you decide where to call.
Take-home doses, telehealth, and the current rules
Federal rules updated in 2024 (the revision to 42 CFR Part 8) expanded take-home methadone, up to a 28-day supply for patients who are stable in treatment, with eligibility decided by the program based on your progress. The same update allowed treatment to start by telehealth and removed older barriers to admission. For buprenorphine, telehealth flexibilities remain in place as of June 2026: you can usually start it through a video or, in many cases, audio-only visit without coming in first. Those flexibilities run through the end of 2026 and are still being finalized, so confirm current options with a provider. Methadone for OUD is still dispensed through an OTP. If you are transferring care or returning after a gap, staying on a steady dose matters, and keeping your methadone dose consistent is part of why continuity is worth protecting. You can also read about long-term methadone treatment if you are planning ongoing care.
Paying for treatment in Louisville
Kentucky Medicaid covers all three medications for opioid use disorder. The program added coverage for methadone dispensed through OTPs in July 2019, and it removed the prior-authorization requirement for the standard buprenorphine-naloxone product, which made it easier to start without an insurance delay. Kentucky Medicaid is delivered through managed care organizations, so the exact network depends on your plan; it is worth confirming that a provider is in-network before your first visit. Private insurance and Medicare also cover MOUD, though private plans vary in which formulations they include. Many programs offer self-pay or sliding-scale options if you are uninsured. The listings on this page can tell you what each provider accepts, and the helpline can help you sort out coverage.
The overdose picture in Jefferson County, and why it points toward treatment
Jefferson County has seen a sharp, recent decline in overdose deaths. According to the Kentucky Office of Drug Control Policy’s 2025 Overdose Fatality Report, 237 county residents died from a drug overdose in 2025, down from 351 in 2024, the second straight year of historic decline, with deaths statewide falling 23 percent in 2025 and 29 percent in 2024. Officials credit record naloxone distribution and broader access to treatment and harm-reduction services. Fentanyl still drives most of these deaths, which is why getting onto an effective medication matters: methadone and buprenorphine both lower the risk of fatal overdose. The numbers are moving in the right direction, and treatment is a large part of why. You can learn more about opioid addiction and how it is treated if you want background before reaching out.
Overdose prevention and naloxone in Louisville
Naloxone, the medication that reverses an opioid overdose, is widely available in Louisville. Kentucky law lets pharmacists dispense it without an individual prescription under a statewide protocol (KRS 217.186), and the state’s findnaloxone.ky.gov registry maps free naloxone sites across Jefferson County. The Louisville Metro Department of Public Health and Wellness runs Harm Reduction Outreach Services, in partnership with the Kentucky Harm Reduction Coalition and UK Target Four, providing free naloxone, overdose-prevention education, fentanyl test strips, and referrals to treatment. Kentucky’s Good Samaritan provisions protect people who call for help during an overdose. If you or someone you know uses opioids, carrying naloxone is a basic safety step, and a return to use is a common, manageable part of recovery, not a failure. For more on the risks, see how methadone overdose risk works and how to stay safe.
Pregnancy, families, and court-involved care
If you are pregnant and have OUD, medication treatment is the recommended standard of care. Both methadone and buprenorphine are used during pregnancy and improve outcomes for parent and baby; stopping opioids suddenly is not advised. Kentucky tracks neonatal outcomes through its Neonatal Abstinence Syndrome Reporting Registry and recommends a Plan of Safe Care to support families, and perinatal programs funded through the Kentucky Opioid Response Effort (KORE), including care at the University of Louisville, work with pregnant and parenting patients. Treatment is protective, and care teams aim to keep families together rather than separate them. Families supporting a loved one can find guidance on how to help someone start and stay in treatment and on methadone during pregnancy. For people entering treatment through a court, probation, or Casey’s Law petition, many programs can assess and admit quickly and document participation when required; the listings here can confirm what each provider accepts.
Common questions about treatment in Louisville
Is methadone or Suboxone better?
Neither is universally better; they suit different people. Methadone is a full opioid agonist dispensed daily at an OTP at first, with take-homes earned over time. Buprenorphine (Suboxone) is a partial agonist that can be prescribed in an office and filled at a pharmacy. The right choice depends on your history, schedule, and what a clinician recommends with you.
Do I have to go to a clinic every day?
At the start of methadone treatment, often yes, but federal rules now allow up to a 28-day take-home supply once you are stable, decided by the program. Buprenorphine and naltrexone are office-based and do not require daily visits.
Can I start treatment the same week?
Often, yes. Some Louisville-area programs offer same-day or next-day intake, and buprenorphine can frequently be started by telehealth. Availability varies by provider, so call the options on this page to ask about timing.
Will my insurance cover it?
Kentucky Medicaid covers all three OUD medications, and Medicare and most private plans cover treatment as well. Confirm that a specific provider is in your plan’s network before your first visit.
Can I get buprenorphine by telehealth in Kentucky?
As of June 2026, yes, including by phone in many cases, without a prior in-person visit. These rules are set through the end of 2026 and are still being finalized, so confirm what is current with a provider.
Last reviewed and disclosures
Last reviewed June 2026.
Sources: Kentucky Office of Drug Control Policy, 2025 Overdose Fatality Report (2026); Kentucky Cabinet for Health and Family Services, Department for Medicaid Services; Kentucky Revised Statutes 217.186 and the Kentucky Office of Drug Control Policy naloxone registry (findnaloxone.ky.gov); Louisville Metro Department of Public Health and Wellness, Harm Reduction Outreach Services; Kentucky Department for Public Health, Neonatal Abstinence Syndrome Reporting Registry (2025); SAMHSA and DEA (42 CFR Part 8, 2024; buprenorphine telemedicine rules, 2025 to 2026); U.S. Food and Drug Administration.
Methadone Centers is a treatment-discovery and education resource, not a treatment provider, and does not offer medical advice. Information here is for general education and is not a substitute for care from a licensed clinician. Decisions about medication and treatment should be made with a qualified provider.
The helpline featured on this site is operated by a paid advertiser. Calls may be routed to a sponsoring treatment provider. Using the helpline is not required to access the providers listed on this page, and you can contact any provider directly.